Radioprotective Effects of Melatonin on Radiation-Induced Cataract
نویسندگان
چکیده
منابع مشابه
Radioprotective Effect of Melatonin on Radiation-Induced Lung Injury and Lipid Peroxidation in Rats
OBJECTIVE Free radicals generated by ionizing radiation attack various cellular components such as lipids. The lung is a very radiosensitive organ and its damage is a doselimiting factor in radiotherapy treatments. Melatonin (MLT), the major product of the pineal gland acts as a radioprotective agent. This study aims to investigate the radioprotective effects of MLT on malondialdehyde (MDA) lev...
متن کاملRadiosensitizing effects of melatonin on radiation induced chromosomal aberration in G2-lymphocytes of breast cancer patients
Background: Radiotherapy is regarded as a standard treatment modality in breast cancer (BC). Radiation causes cellular damage both in cancer and normal cells by inducing DNA-damage and chromosomal aberrations (CA). Different agents were used for ameliorating effects of radiation, mainly antioxidants such as melatonin. Melatonin shows oncostatic properties on human BC. The aim of this study was ...
متن کاملradioprotective effect of melatonin on radiation-induced lung injury and lipid peroxidation in rats
objective: free radicals generated by ionizing radiation attack various cellular components such as lipids. the lung is a very radiosensitive organ and its damage is a doselimiting factor in radiotherapy treatments. melatonin (mlt), the major product of the pineal gland acts as a radioprotective agent. this study aims to investigate the radioprotective effects of mlt on malondialdehyde (mda) le...
متن کاملProtective Effect of Low Dose Melatonin on Radiation-Induced Damage to Rat Liver
Background: Melatonin is a free radical scavenger. It has also antioxidant effects through its stimulatory actions on antioxidant system. Objective: We conducted this study to examine the effect of different oral doses of melatonin on liver tissue. Methods: We used 42 rats—6 rats in each group. Group I served as the control group; group II rats were pretreated with only melatonin; group III w...
متن کاملMelatonin Reduces Cataract Formation and Aldose Reductase Activity in Lenses of Streptozotocin-induced Diabetic Rat
Background: The relationship between the high activity of aldose reductase (AR) and diabetic cataract formation has been previously investigated. The purpose of the present study was to determine the preventing effect of melatonin on streptozotocin (STZ)-induced diabetic cataract in rats.Methods: 34 adult healthy male Sprague-Dawely rats were divided into four groups. Diabetic control and diabe...
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ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 2005
ISSN: 0449-3060,1349-9157
DOI: 10.1269/jrr.46.277